Searchable abstracts of presentations at key conferences in endocrinology

ea0089t10 | Trials In Progress | NANETS2022

Pilot Study of TQ Formula in Combination with Nivolumab and Ipilimumab in Metastatic Gastroenteropancreatic Neuroendocrine Carcinomas (GEP-NECAs)

Mohamed A , Asa SL , Azmi A , Bajor D , Tirumani SH , Selfridge JE , Mahipal A , Ocuin LM , Winter J , Ammori J , Hardacre J , Hoehn R , Chakrabarti S , Rostocil K , Kaseb A

Background: TQ Formula (TQ, C10H12O2), is an oral formulation, derived from the black seed (Nigella sativa, Ranunculaceae family), and has anti-oxidant, anti-angiogenic effects. TQ Formula has been shown to induce significant immune modulatory effects in a recently published Covid-19 study. Previous studies reported blackseed’s apoptotic and anti-proliferative effects of its components on multiple cancer types, including colon, breast and ovarian adenocarcinoma. Our preli...